Our findings suggest that the role of ghrelin in the regulation of human eating is more complex than suspected so far. In addition
to stimulation of appetite, cognitive functions appear to be involved. Exogenous ghrelin appears to be capable in promoting appetite
independently from acute action on leptin.Interestingly in one female patient with night eating syndrome nocturnal ghrelin levels
were distinctly higher than in healthy women.
http://www.mpipsykl.mpg.de/en/research/themes/sleep/steiger_03/index.html
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